Neuro-X seminar: Prof Tomoya Duenki - Emergent Neural Dynamics in Scalable Brain Organoid Networks

Speaker: <a href="https://www.duenkit.com">Prof Tomoya Duenki</a> Organiser: <a href="http://people.epfl.ch/stephanie.lacour">Prof Stéphanie Lacour</a> <p>Reconstructing physiologically relevant neuronal networks in vitro is essential for advancing our understanding of brain development, function, and disease. Human cerebral organoids provide a promising platform, but conventional systems remain limited in structural complexity, connectivity, and scalability for studying large-scale neural dynamics. To address these limitations, we engineered modular organoid networks, termed “connectoids,” in which multiple organoids are connected through guided axon bundles using microfluidic devices. Electrical recordings revealed that increasing network s